If I Told You You Had A Nice Antibody... Trophy in Zero Escape: The Nonary Games

Story locks are plot checkpoints that will not let you pass if you have not gained pertinent information from other routes. Trophy-wise, it doesn't matter if you actually are stopped by these locks when you're playing the game (as opposed to already having the information before hitting the lock in the first place).

The fourth lock is located via the following choices: Cyan / Ally.

To bypass this story lock, you must play the following route: Yellow / Ally / Red, then finish the Laboratory escape sequence.