Spindler's Search Trophy in Prototype 2
Destroy all Lairs.
How to unlock Spindler's Search
Lairs are one of the collectible types in Prototype 2. Once they are in a radius of ~160 feet you will see a symbol on your screen. You need to enter the lair and kill all of the marked targets inside.
There are a total of 9 Lairs. If you go to your collectibles in-game map you can see how many Lairs are in each area and how many you found already. While viewing the map press / to switch between different collectible types. Keep flying close over the streets until you discover the missing lairs.