Overview:
Estimated trophy difficulty: 3/10 (personal estimate)
Offline: 34 (19 9 5 1 )
Online: 0
Approximate amount of time to platinum: 80+ hrs
Minimum number of playthroughs needed: 1
Number of missable trophies: None
Do cheat codes disable trophies? No cheats
Does difficulty affect trophies? No
Roadmap:
NOTE: This version of the guide targets the English version. The trophy list is the same as the Japanese version. If you want the Japanese version of the guide, please visit Ni No Kuni: Wrath of the White Witch Trophy Guide and Roadmap (JP)
As with any JRPG, a heavy portion of your play is going to come after beating the game. The game itself is very simple, and gives you objective stars to tell you where to advance. As long as you follow those stars, you can't get lost. As you progress through the game, make sure you keep your levels high, because the difficulty spikes a bit in the last dungeon. Make sure you are recruiting every Imajinn you can (aim to have 2 of all the first/second forms of each one), and try to make every recipe you find. Pick a few Imajinn that you like, and feed them treats at every possible chance.
Once you've beaten the main game, you should have (at bare minimum):
Out of this World
En Guardian!
Anchors Aweigh
Fly the Friendlier Skies
Wonder Wand
A Tonic for the Djinn
Council Trouncer
You also should have earned:
Familiarizer
Viva the Evolution!
Little Battler Experience
Prima Donna
Gunslinger
Once you've cleared the game, you can focus on all the other aspects. Everything should be done alongside each other. Visit every area, collect the hidden treasure chests, buy tickets at the casino, make 120 recipes, recruit 250 Familiars, clear all errands, and clear the Solosseum Series. It's not as simple as it sounds, but everything is more a matter of time and patience rather than actual effort, so no detail is necessary.
This game comes with its own databases for you to reference to make it easier for you to find what you need, as well. Telling Stone has all the info on Familiars - where they spawn, what they drop, what type they are, which ones you have recruited, etc. He also has a nice checklist of your percentage completion on quests, recipes, etc, and tracks how many hidden treasures you've found. The Compendium book will reveal recipes that may not show up on the pot's list, as well as where to buy any weapons/armor that are not created from recipes.
What Familiars are recommended?
While you can get through the main game with pretty much any Familiar you want, a good tip is to make sure you have a tank Familiar (shield type or armor+hammer) with a taunt for when you need to recover. Decent tanks include Tin-man (found around Hamelin), and Monolith (found around Castaway Cove). Once you've cleared the game, make sure you've cleared all of Derwin's quests to show him specific Familiars, and then find him in Ding Dong Dell for errand 75, which involves you killing 3 boss Familiar around the world. Once you've done this, he gives you 3 Familiar tickets (trade for the Familiar at the Temple of Trials). One of these is Dinoceros, who is insanely strong both on offense and defense. Even at level 1, with decent gear he can easily outdamage everything you've got. He will make all bounty quests and the Solosseum Series significantly easier on you. Just make sure he learns Sling Stone and War Cry, and he'll also make grinding/farming much faster as well (he also can be found in the cliffs north of Al Mamoon.)
[PST Would Like To Thank Akari for this Roadmap]