- Estimated trophy difficulty: 2/10 if you use exploits but 6/10 if you don't (Platinum Difficulty Rating)
- Offline trophies: 54 (1, 3, 2, 48) + 12 (1, 11) for the Challenge Rooms DLC.
- Online trophies: 0
- Approximate amount of time to Platinum: 26-35hrs (Estimated Time to Platinum)
- Minimum number of playthroughs: 1
- Number of missable trophies: 10 - Tonic Collector, Research PhD, Lucky Winner, Found Cohen's Room, Irony, Dealt With Every Little Sister, Little Sister Savior, Historian, Brass Balls and I Chose the Impossible.
- Glitched trophies: Yes, 1 - Research PhD
- Does difficulty affect trophies?: Yes, you have to play on at least Survivor and to get the Platinum and Medium to complete the DLC.
- Do trophies stack?: Yes, the following stacks exist - Global PS3, JP PS3, PS4 Bioshock Collection, EU PS4 Standalone Re-Release and JP PS4 Standalone Re-Release. Also, the difficulty related and Vita-Chamber trophies also stack within the same playthrough if you start on Survivor and disable the Vita-Chambers. You can also get some other trophies by doing certain activities simultaneously.
- Do cheat codes disable trophies?: No cheats available.
Bioshock is a very unique first person shooter that emphasizes the story a little more than the normal FPS. In addition to the normal guns, there are plasmids and tonics that add some special abilities to your character that are used to make combat a little different in this game. Overall, this game isn’t too difficult but people do have some trouble attaining a few trophies. Most of the trophies are collection based but are easy to get by playing through the story. There is no online portion to this game so there is no online grind to worry about.
There are two different methods to go about getting the platinum, one playthrough or two playthroughs. The quickest is one play through but it means playing through on Survivor. All of the trophies can be attained in one play through on Survivor. Even though this is the highest difficulty setting, it isn’t that difficult after the first few levels. Once you get a few plasmids like Hypnotize Big Daddy, Enrage and Security Bullseye, the game gets easier. The toughest part of Survivor is dealing with the Big Daddies. Fortunately, you can go back after you get stronger weapons and better plasmids and deal with the Big Daddies. Each level has one to three Big Daddies in it. Using Hypnotize Big Daddy to set a Big Daddy vs. Big Daddy rumble is an easy way to deal with them. Armor piercing rounds or crossbow bolts are good choices to clean up if the Big Daddy you want to kill still has some health left. Up until just before the fight with the final boss, you can go back to any stage in the game, with the exception of the first stage, "Welcome to Rapture". If you play through on Survivor and intend on getting all the trophies, make sure you set Vita-Chambers to "Off" in the options menu. If you do this, it will ensure that you don’t accidentally use a Vita-Chamber and lose two trophies.
The other method is to go through on Easy and pick up all the trophies not related to difficulty, then go back through on Survivor to pick up the last few. This is obviously much easier but takes longer to get through. The same principles apply as playing on Survivor but you can take on the Big Daddies earlier without a problem.
There are a few trophies that can be missed. Tonic Collector can be missed if you don't pick up enough tonics throughout the game. Some tonics are scattered throughout Rapture, some can be invented at the U-Invent stations and others are obtained by taking research photos. Most though are picked up at Gatherer’s Garden stations. If you're rescuing all of the Little Sisters (which you should be if you're going for the Platinum) then you will get more Adam to pick up more tonics.
Speaking of the Little Sisters, both Little Sister Savior and Dealt With Every Little Sister can both be missed. The first can be missed if you don't take care of one Big Daddy or harvest one instead of rescuing her. You can go back up until just before the fight with the last boss fight if you haven't taken care of all the Big Daddies.
Other trophies that can be missed are Historian, Research PhD, Irony and Found Cohen’s Room. Historian can be missed pretty easily. There are 122 audio diaries scattered around Rapture. The first two audio diaries in "Welcome to Rapture" can be missed and you cannot go back and get these two. There are three in the "Rapture Central Control" level that cannot be gone back to. Once you complete this area, those are lost forever. The other audio diaries you can go back to up until nearly the end. Research PhD can be missed if you take enough photos or if you don't take pictures of security bots, turrets and security cameras since you don't get trophies for those. Take tons of pictures of everything. You get nice bonuses for taking pictures. Ironyand Found Cohen's Room both deal with Sander Cohen. If you kill him after completing his masterpiece, you can't get into his bedroom. If you kill him and don't take a picture of his corpse, you won't get the Irony trophy. Avoid killing him until later in the game, just remember to take that picture of his body.
If you have the PS3 version then missing any trophies and not having a save from before the final fight, will mean having to start a new game since New Game+ (which was added with the Challenge rooms DLC) will disable all trophies but if you have the PS4 release then you can start a new playthrough on NG+ and grab any you missed.
[PST Would Like To Thank olsen77 for this Road Map]